Article

Benzodiazepine receptor binding in Huntington's disease: [11C]Flumazenil uptake measured using positron emission tomography

2000-05-01

Abstract excerpt

We used positron emission tomography and [11C]flumazenil to analyze the benzodiazepine receptor binding in symptomatic and asymptomatic carriers of the Huntington's disease gene. We found an inverse relationship between [11C]flumazenil and [11C]raclopride binding in the putamen of symptomatic patients, and interpret this result as GABA receptor upregulation. We used positron emission tomography and [11C]flumazenil...

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Literature Corpus work: 8d24697a-5e4d-5815-a632-511bbee52d6f
DOI: 10.1002/1531-8249(200005)47:5<644::aid-ana13>3.0.co;2-c

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