Article
Apolipoprotein-e influences aspects of intellectual ability in type 1 diabetes.
Diabetes - 1 Jan 2003
Ferguson Stewart C, Deary Ian J, Perros Petros, Evans Julie C, Ellard Sian, Hattersley Andrew T, Frier Brian M
Abstract excerpt
The epsilon4 allele of the apolipoprotein-E (APOE) gene is associated with poor outcome following various cerebral insults. The relationship between APOE genotype and cognitive function in patients with type 1 diabetes is unknown. In a cross-sectional study of 96 people with type 1 diabetes, subjects were APOE genotyped, previous exposure to severe hypoglycemia was estimated by questionnaire, and cognition was...
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