Article
The associations of apolipoprotein E and angiotensin-converting enzyme polymorphisms and cognitive function in Type 1 diabetes based on an 18-year follow-up of the DCCT cohort.
Diabetic medicine : a journal of the British Diabetic Association - 1 Jan 2010
Jacobson A M, Paterson A D, Ryan C M, Cleary P A, Waberski B H, Weinger K, Musen G, Dahms W, Bayless M, Silvers N, Harth J, Boright A P
Abstract excerpt
AIMS: Specific polymorphisms of the apolipoprotein E (APOE) and angiotensin-converting enzyme (ACE) genes appear to increase risk for Alzheimer's disease and cognitive dysfunction in the general population, yet little research has examined whether genetic factors influence risk of cognitive dysfunction in patients with Type 1 diabetes. The long-term follow-up of the Diabetes Control and Complications...
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