Article
Health-protective and adverse effects of the apolipoprotein E epsilon2 allele in older men.
Journal of the American Geriatrics Society - 1 Mar 2008
Kulminski Alexander M, Ukraintseva Svetlana V, Arbeev Konstantin G, Manton Kenneth G, Oshima Junko, Martin George M, Il'yasova Dora, Yashin Anatoli I
Abstract excerpt
OBJECTIVES: To reexamine a health-protective role of the common apolipoprotein E (APOE) polymorphism focusing on connections between the APOE epsilon2-containing genotypes and impairments in instrumental activities of daily living (IADLs) in older (> or = 65) men and women and to examine how diagnosed coronary heart disease (CHD), Alzheimer's disease, colorectal cancer, macular degeneration, and atherosclerosis...
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