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Article

The ENOS polymorphism is not associated with severity of renal disease in polycystic kidney disease 1.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Jan 2003

Walker Denise, Consugar Mark, Slezak Jeff, Rossetti Sandro, Torres Vicente E, Winearls Christopher G, Harris Peter C

Abstract excerpt

BACKGROUND: The renal phenotype in autosomal dominant polycystic kidney disease (ADPKD) is highly variable. Although genetic and allelic heterogeneity explain part of this variability, significant intrafamilial differences in time to end-stage renal disease (ESRD) indicate that genetic modifiers and the environment influence renal phenotype. Previously, a glutamic acid to aspartic acid polymorphism at residue 298...

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Source

Identifiers

PMID: 12500225
DOI: 10.1053/ajkd.2003.50027

Genes

PKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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