Article
Lack of association of ACE/angiotensinogen genotype with renal function in autosomal dominant polycystic kidney disease.
Genetic testing - 1 Jan 2000
Saggar-Malik A K, Afzal A R, Swissman J S, Bland M, Sagnella G A, Eastwood J B, MacGregor G A, Jeffery S
Abstract excerpt
ACE polymorphisms have recently been shown to associate with worse renal and or cardiovascular outcome, with the D allele widely reported as a risk factor for cardiovascular disease. In autosomal dominant polycystic kidney disease (ADPKD), there are conflicting reports of an association between ACE polymorphisms and disease phenotype. There are no previous reports of any association between angiotensinogen...
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