Article
Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity.
The Journal of biological chemistry - 14 Mar 2003
Pajvani Utpal B, Du Xueliang, Combs Terry P, Berg Anders H, Rajala Michael W, Schulthess Therese, Engel Jürgen, Brownlee Michael, Scherer Philipp E
Abstract excerpt
Acrp30/adiponectin is an adipocyte-specific secretory protein that has recently been implicated as a mediator of systemic insulin sensitivity with liver and muscle as target organs. Acrp30 is found as two forms in serum, as a lower molecular weight trimer-dimer and a high molecular weight complex. Little is know about the regulation and significance of these Acrp30 complexes in serum and about the events that...
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