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Gene expression profiling of subcutaneous adipose tissue reveals new biomarkers in acromegaly

2 Mar 2023

Abstract excerpt

CONTEXT: Active acromegaly is characterized by lipolysis-induced insulin resistance, which suggests adipose tissue (AT) as a primary driver of metabolic aberrations. OBJECTIVE: To study the gene expression landscape in AT in patients with acromegaly before and after disease control in order to understand the changes and to identify disease-specific biomarkers. METHODS: RNA sequencing was performed on paired...

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Share to Cerebrovascular and genetic disorders
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PMID: 36895180
DOI: 10.1093/ejendo/lvad031

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