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Article

TGFBR3L is an inhibin B co-receptor that regulates female fertility

15 Dec 2021

Abstract excerpt

knockout mice exhibit increased FSH levels, ovarian follicle development, and litter sizes. In contrast, female mice lacking both TGFBR3L and betaglycan are infertile. TGFBR3L’s function and cell-specific expression make it an attractive new target for the regulation of FSH and fertility.

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PMID: 34910520
DOI: 10.1126/sciadv.abl4391

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