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Article

Thiopurine methyltransferase genotype distribution in patients with Crohn's disease.

Alimentary pharmacology & therapeutics - 1 Jan 2003

Reuther L O, Sonne J, Larsen N, Dahlerup J F, Thomsen O O, Schmiegelow K

Abstract excerpt

BACKGROUND: Inter-individual response to azathioprine is partly due to inter-individual variation in the thiopurine methyltransferase (TPMT) activity. The TPMT genotype, which reflects the TPMT activity, has previously been studied in healthy Caucasians, with the most common variant allele being TPMT*3A. TPMT genotyping in adult patients with Crohn's disease has never been performed systematically. AIM: To...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12492733
DOI: 10.1046/j.1365-2036.2003.01403.x

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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