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Article

Demographic history and linkage disequilibrium in human populations.

Nature genetics - 1 Dec 1997

Laan M, Pääbo S

Abstract excerpt

In the human genome, linkage disequilibrium (LD)--the non-random association of alleles at chromosomal loci--has been studied mainly in regions surrounding disease genes on affected chromosomes. Consequently, little information is available on the distribution of LD across anonymous genomic regions in the general population. However, demographic history is expected to influence the extent of overall LD across the...

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PMID: 9398845
DOI: 10.1038/ng1297-435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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