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Investigating the Relationship Between Mutations in gyrA and parC Genes and Resistance to Fluoroquinolones in Uropathogenic Escherichia coli Isolates.

Microbial drug resistance (Larchmont, N.Y.) - 1 Oct 2025

Ghaffari Lashkenari Erfan, Mir Maryam Sadat, Mohammadi Mohsen, Javadi Kasra, Halaji Mehrdad

Abstract excerpt

Introduction: Fluoroquinolone resistance in Escherichia coli, particularly uropathogenic E. coli (UPEC), is a growing concern worldwide. This study investigates the association between mutations in the gyrA and parC genes and fluoroquinolone resistance in UPEC isolates from Urine samples in Iran. Materials and Methods: In total, 150 UPEC isolates were collected, and then, 12 ciprofloxacin-resistant isolates were...

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PMID: 40930569
DOI: 10.1177/10766294251377378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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