Article
Investigating the Relationship Between Mutations in gyrA and parC Genes and Resistance to Fluoroquinolones in Uropathogenic Escherichia coli Isolates.
Microbial drug resistance (Larchmont, N.Y.) - 1 Oct 2025
Ghaffari Lashkenari Erfan, Mir Maryam Sadat, Mohammadi Mohsen, Javadi Kasra, Halaji Mehrdad
Abstract excerpt
Introduction: Fluoroquinolone resistance in Escherichia coli, particularly uropathogenic E. coli (UPEC), is a growing concern worldwide. This study investigates the association between mutations in the gyrA and parC genes and fluoroquinolone resistance in UPEC isolates from Urine samples in Iran....
Topics
- Genes, Bacterial
- Drug Resistance, Bacterial
- Uropathogenic Escherichia coli
- Iran
- Urine
- DNA Gyrase
- DNA Topoisomerase IV
- Mutation
- Urinary Tract Infections
- Fluoroquinolones
- Humans
- Cross-Sectional Studies
- Ciprofloxacin
- Anti-Bacterial Agents
- Microbial Sensitivity Tests
- Norfloxacin
- Male
- Female