Article
Mutations in ParC and GyrA of moxifloxacin-resistant and susceptible Mycoplasma genitalium strains.
PloS one - 1 Jan 2018
Hamasuna Ryoichi, Le Phuong Thi, Kutsuna Satoshi, Furubayashi Keiichi, Matsumoto Masahiro, Ohmagari Norio, Fujimoto Naohiro, Matsumoto Tetsuro, Jensen Jorgen Skov
Abstract excerpt
Macrolide or fluoroquinolone-resistant Mycoplasma genitalium is spreading worldwide. We aimed to determine the influence of single nucleotide polymorphisms (SNPs) in the quinolone resistance determining regions (QRDR) of parC and gyrA in cultured M. genitalium strains. In addition, we examined the prevalence of macrolide- and fluoroquinolone resistance mediating mutations in specimens collected from Japanese male...
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