Article
Association of antiretroviral resistance genotypes with response to therapy--comparison of three models.
Antiviral therapy - 1 Sept 2002
Quigg Marlynne, Frost Simon D W, McDonagh Susan, Burns Sheila M, Clutterbuck Daniel, McMillan Alexander, Leen Clifford S, Brown Andrew J Leigh
Abstract excerpt
Genotype-based resistance assays are commonly used to aid treatment in HIV-infected individuals failing antiretroviral therapy. The relationship between genotype and antiretroviral therapy comes mostly from in vitro assays of the response to a single drugs although there is a need for a prediction of clinical response to combination therapy. We have compared three different methods of analysing genotype data as a...
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