Article
Differential Gene Expression in Vascular Smooth Muscle Cells in Primary Atherosclerosis and In Stent Stenosis in Humans
1 Dec 2002
Abstract excerpt
OBJECTIVE: We sought to identify differentially expressed genes in human in stent stenosis (ISS) to provide insights into the mechanism of disease. METHODS AND RESULTS: Using representation difference analysis, we examined differential gene expression between cultured normal human medial vascular smooth muscle cells (VSMCs) and cells from primary atherosclerotic plaques or ISS sites. Specific groups of genes were...
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