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Article

Gene expression signatures, pathways and networks in carotid atherosclerosis

30 Nov 2015

Abstract excerpt

BACKGROUND: Embolism from unstable atheromas in the carotid bifurcation is a major cause of stroke. Here, we analysed gene expression in endarterectomies from patients with symptomatic (S) and asymptomatic (AS) carotid stenosis to identify pathways linked to plaque instability. METHODS: Microarrays were prepared from plaques (n = 127) and peripheral blood samples (n = 96) of S and AS patients. Gene set...

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PMID: 26620734
DOI: 10.1111/joim.12448

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