Investigation into the role of Stmn2 in vascular smooth muscle phenotype transformation during vascular injury via RNA sequencing and experimental validation.

doi:10.1007/s11356-021-15846-7

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Investigation into the role of Stmn2 in vascular smooth muscle phenotype transformation during vascular injury via RNA sequencing and experimental validation.

Environmental science and pollution research international - 1 Jan 2022

Ke Xiao, Guo Wenyu, Peng Yanren, Feng Zongming, Huang Yi-Teng, Deng Ming, Wei Min-Xin, Wang Zan-Xin

Abstract excerpt

This study examined the effects of Stmn2 on phenotype transformation of vascular smooth muscle in vascular injury via RNA sequencing and experimental validation. Total RNA was extracted for RNA sequencing after 1, 3 and 5 days of injury to screen the differentially expressed genes (DEGs). Western blot was used to detect the protein expression of Stmn2 and its associated targets. The morphological changes of...

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PMID: 34389950
DOI: 10.1007/s11356-021-15846-7

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