Article
Molecular cloning of human prostacyclin receptor cDNA and its gene expression in the cardiovascular system.
1 Oct 1994
Abstract excerpt
BACKGROUND: Prostacyclin elicits a potent vasodilation and inhibition of platelet aggregation through binding to its membrane receptor. The impairment of prostacyclin receptor activity is implicated in various human cardiovascular diseases. In the present study, we succeeded in the isolation and characterization of human prostacyclin receptor cDNA and elucidated its gene expression in human tissues. METHODS AND...