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Prostanoid signal transduction and gene expression in the endothelium: Role in cardiovascular diseases

4 Feb 2006

Abstract excerpt

Endothelial cells play an active role in the maintenance of homeostasis. Endothelial injury can give rise to endothelial dysfunction in which the profile of mediators released by endothelial cells is altered. Among these mediators are factors that participate in the development of many cardiovascular disorders. Some of the most important are the prostanoids, which can modulate the progression of atherosclerosis,...

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PMID: 16458868
DOI: 10.1016/j.cardiores.2005.12.020

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