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Article

Multigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis.

International journal of cancer - 10 Feb 2003

Güner Dilek, Sturm Isrid, Hemmati Philipp, Hermann Sandra, Hauptmann Steffen, Wurm Reinhard, Budach Volker, Dörken Bernd, Lorenz Matthias, Daniel Peter T

Abstract excerpt

Deregulation of cell-cycle G(1)-restriction point control by disruption of Rb-pathway components is a frequent event in cancer. In concert with the inactivation of cell death pathways, such events not only contribute to tumor development but also determine the intrinsic and acquired resistance to cancer therapy and, ultimately, disease prognosis. We previously observed that the cyclin-dependent kinase inhibitor...

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PMID: 12478659
DOI: 10.1002/ijc.10850

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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