Article
Ultra-rapid DNA analysis using HyBeacon probes and direct PCR amplification from saliva.
Molecular and cellular probes - 1 Oct 2002
French D J, Archard C L, Andersen M T, McDowell D G
Abstract excerpt
We describe a novel probe technology, termed HyBeacons, which provides a new homogeneous method for fluorescence-based sequence detection and allele discrimination. Employing a single nucleotide polymorphism located in the N-acetyltransferase 2 gene as a model system, we demonstrate the utility of HyBeacon probes for rapid and reliable sequence analysis. We also demonstrate that homozygous and heterozygous...
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