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Article

Detection of human DNA mutations with nonradioactive, allele-specific oligonucleotide probes.

Pharmacogenetics - 1 Apr 1992

Hajra A, Sorenson R C, La Du B N

Abstract excerpt

We describe a method of detecting human DNA mutations with nonradioactive, biotinylated allele-specific oligonucleotide probes. This method can detect seven different mutations in the butyrylcholinesterase, cystic fibrosis, and N-acetyltransferase genes under identical assay conditions. This indicates that it may be used to detect mutations responsible for a wide variety of genetic diseases and pharmacogenetic...

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Identifiers

PMID: 1302045
DOI: 10.1097/00008571-199204000-00005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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