Article
A comprehensive genetic association and functional study of TNF in schizophrenia risk.
Schizophrenia research - 1 Mar 2006
Shirts Brian H, Bamne Mikhil, Kim Jung Jin, Talkowski Michael, Wood Joel, Yolken Robert, Nimgaonkar Vishwajit L
Abstract excerpt
In view of prior reports suggesting associations between polymorphisms of the tumor necrosis factor gene (TNF) and schizophrenia, we sequenced all exons, introns and 7 kb flanking sequence at TNF in DNA pooled from 125 Caucasian schizophrenia cases and 200 controls. We identified 18 SNPs of which we selected and genotyped 8 among 244 cases and 276 controls. We detected no significant genotype or haplotype...
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