Article
ETS1 transactivates the human GM-CSF promoter in Jurkat T cells stimulated with PMA and ionomycin.
Oncogene - 16 Nov 1995
Thomas R S, Tymms M J, Seth A, Shannon M F, Kola I
Abstract excerpt
Activation of T helper cells results in coordinate expression of a number of cytokines involved in differentiation, proliferation and activation of the haematopoietic system. Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one such cytokine whose increased expression results partly f...
Topics
- Base Sequence
- Granulocyte-Macrophage Colony-Stimulating Factor
- Humans
- Ionomycin
- Molecular Sequence Data
- Mutation
- Oncogene Proteins
- Promoter Regions, Genetic
- Proto-Oncogene Proteins c-ets
- Recombinant Proteins
- Stimulation, Chemical
- T-Lymphocytes
- Tetradecanoylphorbol Acetate
- Transcription Factors
- Transcription, Genetic
- Transcriptional Activation
- Transfection