Article
Analysis of Complement C3 Gene Reveals Susceptibility to Severe Preeclampsia
29 May 2017
Abstract excerpt
Preeclampsia is a common vascular disease of pregnancy with genetic predisposition. Dysregulation of the complement system has been implicated, but molecular mechanisms are incompletely understood. In this study, we determined the potential linkage of severe preeclampsia to the most central complement gene, C3. Three cohorts of Finnish patients and controls were recruited for a genetic case-control study....
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