Article
A genome-wide scan for preeclampsia in the Netherlands.
European journal of human genetics : EJHG - 1 Oct 2001
Lachmeijer A M, Arngrímsson R, Bastiaans E J, Frigge M L, Pals G, Sigurdardóttir S, Stéfansson H, Pálsson B, Nicolae D, Kong A, Aarnoudse J G, Gulcher J R, Dekker G A, ten Kate L P, Stéfansson K
Abstract excerpt
Preeclampsia, hallmarked by de novo hypertension and proteinuria in pregnancy, has a familial tendency. Recently, a large Icelandic genome-wide scan provided evidence for a maternal susceptibility locus for preeclampsia on chromosome 2p13 which was confirmed by a genome scan from Australia and New Zealand (NZ). The current study reports on a genome-wide scan of Dutch affected sib-pair families. In total 67 Dutch...
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