Autosomal mutation in somatic cells of the mouse.

Abstract excerpt

Tumor suppressor genes are located on autosomal chromosomes. Therefore, an understanding of how cancer-related mutations occur in somatic cells requires a detailed understanding of spontaneous and induced autosomal mutagenesis. This review will present recent advances in the study of how autosomal mutations form in somatic cells by focusing on the mouse Aprt and Tk model systems that have been developed to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adenine Phosphoribosyltransferase
• Share to Ataxia Telangiectasia Mutated Proteins
• Share to DNA Repair Enzymes