The effect of circadian rhythm on prolactin/PRLR-mediated intracellular signaling profiles in vivo and in vitro.

doi:10.1016/j.tice.2021.101570

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Article

The effect of circadian rhythm on prolactin/PRLR-mediated intracellular signaling profiles in vivo and in vitro.

Tissue & cell - 1 Dec 2021

Yuzhen Chen, Zheng Fudong

Abstract excerpt

The circadian molecular Clock is an internal time-keeping system, which regulates various physiological processes. The circadian Clock may be involved in all biological processes. The circadian Clock is closely related to prolactin's activities. However, until now, the effect of circadian Clock dysregulation on PRL's bioactivities remains unclear. Clock protein is an essential component in circadian Clock and...

Topics

Animals
CLOCK Proteins
Cell Line
Circadian Rhythm
Down-Regulation
Epithelial Cells
Intracellular Space
Janus Kinase 2
Mice, Inbred C57BL
Mice, Knockout
Phenotype
Prolactin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Messenger

Receptors, Prolactin

STAT5 Transcription Factor

Signal Transduction

Suppressor of Cytokine Signaling 1 Protein

Suppressor of Cytokine Signaling 3 Protein

Source

Open in PubMed

Identifiers

PMID: 34343759
DOI: 10.1016/j.tice.2021.101570

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-34343759-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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