Article
Variants in the PPARgamma gene affect fatty acid and glycerol metabolism in familial combined hyperlipidemia.
Molecular genetics and metabolism - 1 Nov 2003
Eurlings Petra M H, van der Kallen Carla J H, Vermeulen Vicky M M-J, de Bruin Tjerk W A
Abstract excerpt
Familial combined hyperlipidemia (FCHL) is a common genetic lipid disorder characterized by premature coronary artery disease, dyslipidemia, insulin resistance, and impaired adipose tissue free fatty acid (FFA) metabolism. Increased adipose tissue FFA flux towards the liver may, in part, contribu...
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