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Article

Familial combined hyperlipidemia: An overview of the underlying molecular mechanisms and therapeutic strategies

4 Jul 2019

Abstract excerpt

Among different types of dyslipidemia, familial combined hyperlipidemia (FCHL) is the most common genetic disorder, which is characterized by at least two different forms of lipid abnormalities: hypercholesterolemia and hypertriglyceridemia. FCHL is an important cause of cardiovascular diseases. FCHL is a heterogeneous condition linked with some metabolic defects that are closely associated with FCHL. These...

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PMID: 31271707
DOI: 10.1002/iub.2073

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