Article
Genetic dissection of familial combined hyperlipidemia.
Molecular genetics and metabolism - 1 Jan 2000
Eurlings P M, van der Kallen C J, Geurts J M, van Greevenbroek M M, de Bruin T W
Abstract excerpt
Familial combined hyperlipidemia (FCHL) is the most common genetic hyperlipidemia in man. FCHL is characterized by familial clustering of hyperlipidemia and clinical manifestations of premature coronary heart disease, i.e., before the age of 60. Although FCHL was delineated about 25 years ago, at present the FCHL phenotype and its complex genetics are not fully understood. Initially, the familial aggregation of...
Topics
- Animals
- Disease Models, Animal
- Genetic Predisposition to Disease
- Humans
- Hyperlipidemia, Familial Combined