Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical application of oligonucleotide probe array for full-length gene sequencing of TP53 in colon cancer.

Oncology - 1 Jan 2003

Takahashi Yasuo, Ishii Yukimoto, Nagata Toshihito, Ikarashi Masahito, Ishikawa Koichi, Asai Satoshi

Abstract excerpt

OBJECTIVE: TP53 mutations are the most frequent genetic alterations in colon cancer. We studied whether the recently developed oligonucleotide microarray technique, GeneChip p53 assay, can be applied to sensitive detection of TP53 gene mutations in surgical specimens from colon cancer patients. METHODS: TP53 gene mutations in exons 2-11 in 20 colon cancers and the corresponding histopathologically normal mucosa...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colonic Neoplasms
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Genes, p53

Share to Immunoenzyme Techniques

Share to Oligonucleotide Array Sequence Analysis

Share to Oligonucleotide Probes

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 12457032
DOI: 10.1159/000066510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical application of oligonucleotide probe array for full-length gene sequencing of TP53 in colon cancer.PMID 12457032Read ↗

Identification of TP53 mutations in human cancers using oligonucleotide microarrays.Semantic proximity Read ↗

Evaluation of oligonucleotide arrays for sequencing of the p53 gene in DNA from formalin-fixed, paraffin-embedded breast cancer specimens.Semantic proximity Read ↗

Oligonucleotide probe array for p53 gene alteration analysis in DNA from formalin-fixed paraffin-embedded breast cancer tissues.Semantic proximity Read ↗

Evaluating the arrayed primer extension resequencing assay of TP53 tumor suppressor gene.Semantic proximity Read ↗

A comprehensive system to explore p53 mutations.Semantic proximity Read ↗

Development and applications of a beta-catenin oligonucleotide microarray: beta-catenin mutations are dominantly found in the proximal colon cancers with microsatellite instability.Semantic proximity Read ↗

Prognostic Value of p53 Genetic Changes in Colorectal CancerSemantic proximity Read ↗

p53 alterations are associated with improved prognosis in distal colonic carcinomas.Semantic proximity Read ↗

Oligonucleotide microarrays with high discriminating power for the detection of single nucleotide variations in the p53 gene.Semantic proximity Read ↗

Impact of alterations affecting the p53 pathway in bladder cancer on clinical outcome, assessed by conventional and array-based methods.Semantic proximity Read ↗

[Application of oligonucleotide microarray primer extension to detection of p53 single nucleotide polymorphisms].Semantic proximity Read ↗

Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.