Article
Potential role of CCND1 G870A genotype as a predictor for urothelial carcinoma susceptibility and muscle-invasiveness in Taiwan.
The Chinese journal of physiology - 30 Jun 2011
Lin Hui-Hui, Ke Hung-Lung, Hsiao Kuang-Hung, Tsai Chia-Wen, Wu Wen-Jeng, Bau Da-Tian, Chang Lin-Li
Abstract excerpt
The cell cycle regulator cyclin D1 (CCND1) is thought to play a major role in the transition of cell cycle from G1 to S phase. It is known that a common CCND1 G870A genotype is associated with bladder cancer in Japan and China, but not in the Western World. There is neither a report about its role in Taiwan's population, nor its genetic role of CCND1 G870A in another worldwide urothelial cancer, upper tract...
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