Article
Elevated risk of colorectal cancer associated with the AA genotype of the cyclin D1 A870G polymorphism in an Indian population.
Journal of cancer research and clinical oncology - 1 Mar 2006
Jiang Jing, Wang Jingweng, Suzuki Sadao, Gajalakshmi Vendhan, Kuriki Kiyonori, Zhao Yang, Nakamura Seiichi, Akasaka Susumu, Ishikawa Hideki, Tokudome Shinkan
Abstract excerpt
PURPOSE: To investigate whether the common cyclin D1 (CCND1) A870G polymorphism is a risk factor for colorectal cancer (CRC) in an Indian population. METHODS: In this study, 301 newly diagnosed CRC patients and 291 healthy control subjects were genotyped by the PCR-RFLP method. Genotype frequencies were compared between cases and controls, and the association of genotypes with CRC was studied. RESULTS: The CCND1...
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