Article
The p34cdc2-related cyclin-dependent kinase 11 interacts with the p47 subunit of eukaryotic initiation factor 3 during apoptosis.
The Journal of biological chemistry - 14 Feb 2003
Shi Jiaqi, Feng Yongmei, Goulet Anne-Christine, Vaillancourt Richard R, Sachs Nancy A, Hershey John W, Nelson Mark A
Abstract excerpt
Cyclin-dependent kinase 11 (CDK11; also named PITSLRE) is part of the large family of p34(cdc2)-related kinases whose functions appear to be linked with cell cycle progression, tumorigenesis, and apoptotic signaling. However, substrates of CDK11 during apoptosis have not been identified. We used a yeast two-hybrid screening strategy and identified eukaryotic initiation factor 3 p47 protein (eIF3 p47) as an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
