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Article

Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism.

British journal of clinical pharmacology - 1 Nov 2002

Yoshida Ryoko, Nakajima Miki, Watanabe Yuki, Kwon Jun-Tack, Yokoi Tsuyoshi

Abstract excerpt

AIMS: Previously, we determined the phenotyping of in vivo nicotine metabolism and the genotyping of the CYP2A6 gene (CYP2A6*1 A, CYP2A6*1B, CYP2A6*2, CYP2A6*3, CYP2A6*4 and CYP2A6*5 ) in 92 Japanese and 209 Koreans. In the study, we found one Korean and four Japanese subjects genotyped as CYP2A6*1B/CYP2A6*4 who revealed impaired nicotine metabolism, although other many heterozygotes of CYP2A6*4 demonstrated...

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Identifiers

PMID: 12445030
DOI: 10.1046/j.1365-2125.2002.01667.x
PMCID: PMC1874463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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