Article
The effect of the CYP1A2 *1F mutation on CYP1A2 inducibility in pregnant women.
British journal of clinical pharmacology - 1 Nov 2002
Nordmark Anna, Lundgren Stefan, Ask Birgitta, Granath Fredrik, Rane Anders
Abstract excerpt
AIMS: To investigate the influence of the CYP1A2*1F mutation on CYP1A2 activity in smoking and nonsmoking pregnant women. METHODS: Pregnant women (n = 904) who served as control subjects in a case-control study of early fetal loss were investigated. They were phenotyped for CYP1A2 using dietary caffeine and the urinary ratio AFMU + 1X + 1 U/1,7 U. An assay for CYP1A2*1F using 5'-nuclease assay (Taqman) was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
