Article
Maternal cigarette smoking, metabolic gene polymorphism, and infant birth weight.
JAMA - 9 Jan 2002
Wang Xiaobin, Zuckerman Barry, Pearson Colleen, Kaufman Gary, Chen Changzhong, Wang Guoying, Niu Tianhua, Wise Paul H, Bauchner Howard, Xu Xiping
Abstract excerpt
CONTEXT: Little is known about genetic susceptibility to cigarette smoke in relation to adverse pregnancy outcomes. OBJECTIVE: To investigate whether the association between maternal cigarette smoking and infant birth weight differs by polymorphisms of 2 maternal metabolic genes: CYP1A1 and GSTT1. DESIGN, SETTING, AND PARTICIPANTS: Case-control study conducted in 1998-2000 among 741 mothers (174 ever smokers and...
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