Article
Association of cytochrome P450 1B1 polymorphism with first-trimester miscarriage.
Fertility and sterility - 1 Nov 2006
Karypidis Anna-Helena, Söderström Torbjörn, Nordmark Anna, Granath Fredrik, Cnattingius Sven, Rane Anders
Abstract excerpt
OBJECTIVE: To determine whether the cytochrome P450 1B1 (CYP1B1) Val432Leu polymorphism is associated with risk of miscarriage. We also analyzed the possible interaction between this polymorphism and caffeine intake. DESIGN: The population-based case-control study included 507 women with miscarriage in the first trimester of pregnancy and 908 controls with a normal first-trimester pregnancy. The controls were...
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