Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phase variation in meningococcal lipooligosaccharide biosynthesis genes.

FEMS immunology and medical microbiology - 13 Dec 2002

Berrington A W, Tan Y-C, Srikhanta Y, Kuipers B, van der Ley P, Peak I R A, Jennings M P

Abstract excerpt

Neisseria meningitidis expresses a range of lipooligosaccharide (LOS) structures, comprising of at least 13 immunotypes (ITs). Meningococcal LOS is subject to phase variation of its terminal structures allowing switching between ITs, which is proposed to have functional significance in disease. The objectives of this study were to investigate the repertoire of structures that can be expressed in clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Lipopolysaccharides

Share to Meningococcal Infections

Share to Neisseria meningitidis

Share to Polymerase Chain Reaction

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 12443826
DOI: 10.1111/j.1574-695X.2002.tb00633.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phase variation in meningococcal lipooligosaccharide biosynthesis genes.PMID 12443826Read ↗

The genetic basis of the phase variation repertoire of lipopolysaccharide immunotypes in Neisseria meningitidis.Semantic proximity Read ↗

Immunologic and genetic characterization of lipooligosaccharide variants in a Neisseria meningitidis serogroup C strain.Semantic proximity Read ↗

Lipooligosaccharide Structures of Invasive and Carrier Isolates of Neisseria meningitidis Are Correlated with Pathogenicity and CarriageSemantic proximity Read ↗

Repeat-associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58.Semantic proximity Read ↗

Phase variation of lipopolysaccharide directs interconversion of invasive and immuno-resistant phenotypes of Neisseria gonorrhoeae.Semantic proximity Read ↗

Meningococcal core and accessory phasomes vary by clonal complex.Semantic proximity Read ↗

Phase variable changes in genes lgtA and lgtC within the lgtABCDE operon of Neisseria gonorrhoeae can modulate gonococcal susceptibility to normal human serumSemantic proximity Read ↗

Phase variation of DNA methyltransferases and the regulation of virulence and immune evasion in the pathogenic NeisseriaSemantic proximity Read ↗

Lipooligosaccharide structure contributes to multiple steps in the virulence of Neisseria meningitidis.Semantic proximity Read ↗

In-silico prediction and deep-DNA sequencing validation indicate phase variation in 115 Neisseria meningitidis genes.Semantic proximity Read ↗

Comparative whole-genome analyses reveal over 100 putative phase-variable genes in the pathogenic Neisseria spp.Semantic proximity Read ↗

Prevalence and phase variable expression status of two autotransporters, NalP and MspA, in carriage and disease isolates of Neisseria meningitidis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.