Article
Prevalence and phase variable expression status of two autotransporters, NalP and MspA, in carriage and disease isolates of Neisseria meningitidis.
PloS one - 1 Jan 2013
Oldfield Neil J, Matar Suzan, Bidmos Fadil A, Alamro Mohammed, Neal Keith R, Turner David P J, Bayliss Christopher D, Ala'aldeen Dlawer A A
Abstract excerpt
Neisseria meningitidis is a human nasopharyngeal commensal capable of causing life-threatening septicemia and meningitis. Many meningococcal surface structures, including the autotransporter proteins NalP and MspA, are subject to phase variation (PV) due to the presence of homopolymeric tracts within their coding sequences. The functions of MspA are unknown. NalP proteolytically cleaves several surface-located...
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