Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phase variation of DNA methyltransferases and the regulation of virulence and immune evasion in the pathogenic Neisseria

14 Jul 2017

Abstract excerpt

The pathogenic Neisseria provide textbook examples of phase variation: the high frequency, random and reversible switching of gene expression. Typically, phase variable gene expression is observed in genes required for the expression of surface proteins and carbohydrate structures. All Neisseria gonorrhoeae and N. meningitidis strains also express phase variable DNA methyltransferases that are components of DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Infections and Vaccines
Share to Pneumonia and Respiratory Infections
Share to Reproductive tract infections research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28859312
DOI: 10.1093/femspd/ftx080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phase variation of DNA methyltransferases and the regulation of virulence and immune evasion in the pathogenic NeisseriaPMID 28859312Read ↗

Epigenetic Regulation of Virulence and Immunoevasion by Phase-Variable Restriction-Modification Systems in Bacterial PathogensSemantic proximity Read ↗

Phasevarions mediate random switching of gene expression in pathogenic Neisseria.Semantic proximity Read ↗

Distribution of the type III DNA methyltransferases modA, modB and modD among Neisseria meningitidis genotypes: implications for gene regulation and virulenceSemantic proximity Read ↗

Phasevarions of bacterial pathogens – phase-variable epigenetic regulators evolving from restriction–modification systemsSemantic proximity Read ↗

A novel epigenetic regulator associated with the hypervirulent Neisseria meningitidis clonal complex 41/44.Semantic proximity Read ↗

Origin of the diversity in DNA recognition domains in phasevarion associated modA genes of pathogenic Neisseria and Haemophilus influenzae.Semantic proximity Read ↗

Actinobacillus pleuropneumoniae encodes multiple phase-variable DNA methyltransferases that control distinct phasevarionsSemantic proximity Read ↗

Mismatch repair and the regulation of phase variation in Neisseria meningitidis.Semantic proximity Read ↗

Phase-variable Type I methyltransferase M.NgoAV from Neisseria gonorrhoeae FA1090 regulates phasevarion expression and gonococcal phenotypeSemantic proximity Read ↗

Meningococcal core and accessory phasomes vary by clonal complex.Semantic proximity Read ↗

A random six-phase switch regulates pneumococcal virulence via global epigenetic changesSemantic proximity Read ↗

Prevalence and phase variable expression status of two autotransporters, NalP and MspA, in carriage and disease isolates of Neisseria meningitidis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.