Article
Clonal origin of multifocal renal cell carcinoma as determined by microsatellite analysis.
The Journal of urology - 1 Dec 2002
Junker Kerstin, Thrum Katharina, Schlichter Andreas, Müller Gabriele, Hindermann Winfried, Schubert Joerg
Abstract excerpt
PURPOSE: The reported incidence of satellite tumor lesions in renal cell carcinoma (7% to 25%) suggests that there is a risk of local recurrence after nephron sparing surgery. It remains largely unknown whether small satellite tumors show malignant features and whether they are metastases from the primary tumor. Therefore, we determined the clonality of multifocal tumors by molecular genetic analysis. MATERIALS...
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