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Article

Allele frequency of three functionally active polymorphisms of the MDR-1 gene in high-risk HIV-negative and HIV-positive Caucasians.

AIDS (London, England) - 22 Nov 2002

Ifergan Igal, Bernard Nicole F, Bruneau Julie, Alary Michel, Tsoukas Christos M, Roger Michel

Abstract excerpt

Recent data suggest that MDR-1 expression may affect HIV-1 infectivity by modulating the immune response and its cellular permissiveness. We investigated whether three functional MDR-1 polymorphims (T-129C, G2677T/A, C3435T) were associated with the risk of infection in 137 Caucasians highly expo...

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Identifiers

PMID: 12441809
DOI: 10.1097/00002030-200211220-00017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12441809-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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