Article
Allelic frequencies of host genetic variants influencing susceptibility to HIV-1 infection and disease in South African populations.
AIDS (London, England) - 10 Mar 2000
Williamson C, Loubser S A, Brice B, Joubert G, Smit T, Thomas R, Visagie M, Cooper M, van der Ryst E
Abstract excerpt
OBJECTIVES: Limited information is available on the prevalence in African populations of host genetic polymorphisms conferring resistance to HIV-1 infection and disease. The objective of this study was to determine the allelic frequencies in South African populations of the chemokine receptor gene variants CCR5delta32, CCR5m303 and CCR2b-641 and the CXCR4 ligand gene variant SDF1-3'A. METHOD: Cross-sectional...
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