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Allelic frequencies of host genetic variants influencing susceptibility to HIV-1 infection and disease in South African populations.

AIDS (London, England) - 10 Mar 2000

Williamson C, Loubser S A, Brice B, Joubert G, Smit T, Thomas R, Visagie M, Cooper M, van der Ryst E

Abstract excerpt

OBJECTIVES: Limited information is available on the prevalence in African populations of host genetic polymorphisms conferring resistance to HIV-1 infection and disease. The objective of this study was to determine the allelic frequencies in South African populations of the chemokine receptor gene variants CCR5delta32, CCR5m303 and CCR2b-641 and the CXCR4 ligand gene variant SDF1-3'A. METHOD: Cross-sectional...

Topics

Alleles
Base Sequence
Black People
DNA Primers
Gene Frequency
Genetic Predisposition to Disease
HIV Infections
HIV-1
Humans
Polymorphism, Genetic
Receptors, CCR5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, CXCR4

South Africa

White People

Source

Identifiers

PMID: 10770549
DOI: 10.1097/00002030-200003100-00020

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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