Article
Low-penetrance genes and their involvement in colorectal cancer susceptibility.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2002
de Jong Mirjam M, Nolte Ilja M, te Meerman Gerard J, van der Graaf Winette T A, de Vries Elisabeth G E, Sijmons Rolf H, Hofstra Robert M W, Kleibeuker Jan H
Abstract excerpt
This report focuses on low-penetrance genes that are associated with colorectal adenoma and/or cancer or that are in strong linkage disequilibrium with colorectal adenoma and/or cancer causing variants. A pooled analysis was performed for 30 polymorphisms in 20 different genes that have been reported in more than one colorectal adenoma or cancer study. An association with colorectal cancer was found for seven...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.