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Article

Serotonin transporter gene polymorphism influences age at onset in patients with bipolar affective disorder.

Neuroscience letters - 6 Dec 2002

Bellivier Frank, Leroux Maÿliss, Henry Chantal, Rayah Fadila, Rouillon Frédéric, Laplanche Jean-Louis, Leboyer Marion

Abstract excerpt

Serotonin transporter (SLC6A4) gene polymorphism is associated with several behavioral and psychiatric traits. In bipolar affective disorder, two polymorphisms of the SLC6A4 gene, a variable number of tandem repeats in the second intron and a 44 bp insertion/deletion in the serotonin transporter gene linked polymorphic region (5-HTTLPR), have been extensively studied. The findings are conflicting possibly because...

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PMID: 12431765
DOI: 10.1016/s0304-3940(02)01029-7

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