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Article

DRD4 VNTR polymorphism and age at onset of severe mental illnesses.

Neuroscience letters - 21 Jun 2012

Gonçalves Vanessa Faria, Tiwari Arun K, de Luca Vincenzo, Kong Say Li, Zai Clement, Tampakeras Maria, Mackenzie Bronwyn, Sun Lei, Kennedy James L

Abstract excerpt

A large number of studies has investigated the hypothesis that DRD4 48 bp variable number of tandem repeat (VNTR) polymorphism is involved in the etiology of schizophrenia and bipolar disorder. However, the results are inconsistent likely due to genetic and phenotypic heterogeneity. Age at onset (AAO) is considered an important alternate phenotype for genetic investigations of psychiatric disorders. In the...

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Source

Identifiers

PMID: 22543114
DOI: 10.1016/j.neulet.2012.04.027

Genes

DRD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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