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Characteristics and profiles of bipolar I patients according to age-at-onset: findings from an admixture analysis.

Journal of affective disorders - 25 Sept 2013

Azorin Jean-Michel, Bellivier Frank, Kaladjian Arthur, Adida Marc, Belzeaux Raoul, Fakra Eric, Hantouche Elie, Lancrenon Sylvie, Golmard Jean-Louis

Abstract excerpt

BACKGROUND: Many studies have used admixture analysis to separate age-at-onset (AAO) subgroups in bipolar patients, but few have looked at the phenomenological characteristics of these subgroups, in order to find out phenotypic markers. METHODS: Admixture analysis was applied to identify the model best fitting the observed AAO distribution of a sample of 1082 consecutive DSM-IV bipolar I manic inpatients who were...

Topics

Adult
Age of Onset
Bipolar Disorder
Comorbidity
Diagnostic and Statistical Manual of Mental Disorders
Female
France
Humans
Male
Middle Aged
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Research Design

Retrospective Studies

Substance-Related Disorders

Suicide, Attempted

Young Adult

Source

Identifiers

PMID: 23769605
DOI: 10.1016/j.jad.2013.05.026

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