Article
Characteristics and profiles of bipolar I patients according to age-at-onset: findings from an admixture analysis.
Journal of affective disorders - 25 Sept 2013
Azorin Jean-Michel, Bellivier Frank, Kaladjian Arthur, Adida Marc, Belzeaux Raoul, Fakra Eric, Hantouche Elie, Lancrenon Sylvie, Golmard Jean-Louis
Abstract excerpt
BACKGROUND: Many studies have used admixture analysis to separate age-at-onset (AAO) subgroups in bipolar patients, but few have looked at the phenomenological characteristics of these subgroups, in order to find out phenotypic markers. METHODS: Admixture analysis was applied to identify the model best fitting the observed AAO distribution of a sample of 1082 consecutive DSM-IV bipolar I manic inpatients who were...
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