Article
Gene for susceptibility to diabetic nephropathy in type 2 diabetes maps to 18q22.3-23.
Kidney international - 1 Dec 2002
Vardarli Irfan, Baier Leslie J, Hanson Robert L, Akkoyun Imren, Fischer Christine, Rohmeiss Peter, Basci Ali, Bartram Claus R, Van Der Woude Fokko J, Janssen Bart
Abstract excerpt
BACKGROUND: Diabetic nephropathy is the major cause of end-stage renal failure in patients with diabetes mellitus types 1 and 2. Epidemiological studies have suggested a genetic susceptibility to diabetic nephropathy. The aim of this study was to localize the gene(s) responsible for susceptibility to diabetic nephropathy. METHODS: A genetic linkage analysis was performed in 18 large Turkish families with type 2...
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